look ahead diabetes prevention program

The trial also recruited other groups at high risk for type 2 diabetes, including people ages 60 and older, women with a history of gestational diabetes, and people with a parent, brother, sister, or child who had type 2 diabetes. The DPP Lifestyle Change Program was effective for all participating racial and ethnic groups and both men and women. J Gerontol A Biol Sci Med Sci. Rockette-Wagner B, Edelstein S, Venditti EM, Reddy D, Bray GA, Carrion-Petersen ML, Dabelea D, Delahanty LM, Florez H, Franks PW, Montez MG, Rubin R, Kriska AM; Diabetes Prevention Program Research Group. Epub 2019 Jul 18. Diabetologia. N Engl J Med. This collection, Diabetes and Exercise, discusses the extent of the problem of diabetes and sedentary lifestyle and presents a compelling rationale for the importance of increased physical activity and exercise in persons with diabetes. Goldberg R, Temprosa M, Otvos J, Brunzell J, Marcovina S, Mather K, Arakaki R, Watson K, Horton E, Barrett-Connor E. Lifestyle and metformin treatment favorably influence lipoprotein subfraction distribution in the Diabetes Prevention Program. Found inside – Page 20Diabetes Care 19:341–349, 1996 Kirk AF, Mutrie N, Macintyre PD, ... JG: Physical activity in individuals at risk for diabetes: Diabetes Prevention Program. N Engl J Med. Diabetes Prevention Program Research Group. Diabetes Care. Diabet Med. wk −1 because of the reported findings that higher levels of PA may be associated with greater weight loss maintenance . Key challenges ahead include: Program availability, engagement, participation and reimbursement Diabetes Therapy, 9, 583-612. Dr. BackgroundThe Diabetes Prevention Program (DPP) and Look AHEAD studies demonstrated that modest weight loss and increased physical activity can significantly reduce the incidence of diabetes among overweight individuals with prediabetes. Look AHEAD, a randomized, controlled, multicenter trial, was designed to determine whether an Intensive Lifestyle Intervention to reduce weight and increase physical activity reduces cardiovascular morbidity and mortality in overweight volunteers with type 2 diabetes compared to the Diabetes … New Diabetes Prevention Program Is a Weight-Loss Plan in Disguise. Found inside – Page 135Diabetes Prevention Program Research Group. ... cardiovascular risk factors in individuals with type 2 diabetes: four year results of the Look AHEAD trial. The 10-year cost-effectiveness of lifestyle intervention or metformin for diabetes prevention: an intent-to-treat analysis of the DPP/DPPOS. Diabetes Care. DeBoer MD, Filipp SL, Gurka MJ. Aroda VR, Knowler WC, Crandall JP, Perreault L, Edelstein SL, Jeffries SL, Molitch ME, Pi-Sunyer X, Darwin C, Heckman-Stoddard BM, Temprosa M, Kahn SE, Nathan DM; Diabetes Prevention Program Research Group. Goldberg RB, Temprosa M, Haffner S, Orchard TJ, Ratner RE, Fowler SE, Mather K, Marcovina S, Saudek C, Matulik MJ, Price D; Diabetes Prevention Program Research Group. After about 3 years, the DPP showed that participants in the DPP Lifestyle Change Program lowered their chances of developing type 2 diabetes by 58 percent compared with participants who took a placebo (a pill without medicine). Two-thirds of US adults are overweight or obese , and excess body weight is a risk factor for type 2 diabetes and cardiovascular disease (CVD) . In the Look AHEAD study, a large multicenter trial examining the effects of an intensive lifestyle intervention (ILI) on cardiovascular events in T2DM, the first 4 years of the ILI treatment led to a 48% reduction in limitations with specific mobility-related activities compared with diabetes support and education (DSE) . Qual Life Res. 2015 Jan;38(1):51-8. doi: 10.2337/dc14-0886. Ryan DH, Espeland MA, Foster GD, et al. 2013 Dec;36(12):4173-5. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Genetic predictors of weight loss and weight regain after intensive lifestyle modification, metformin treatment, or standard care in the Diabetes Prevention Program. Found inside – Page 238Diabetes Prevention Program Research Group, “10-Year Follow-up of Diabetes ... The Look AHEAD Research Group, “Eight-Year Weight Losses with an Intensive ... Start with a 9-inch dinner plate (about the length of a business envelope): Fill half with nonstarchy vegetables, such as salad, green beans, broccoli, cauliflower, cabbage, and carrots. The Look AHEAD (Action for Health in Diabetes) trial was a landmark, multicenter, randomized clinical trial that examined whether an intensive lifestyle intervention would reduce the risk of cardiovascular disease among 5,145 patients with T2DM and overweight or obesity. Impact of Lifestyle and Metformin Interventions on the Risk of Progression to Diabetes and Regression to Normal Glucose Regulation in Overweight or Obese People With Impaired Glucose Regulation. Am J Clin Nutr 2017 Dec;106(6):1337-1346. Replication of the Association of BDNF and MC4R Variants With Dietary Intake in the Diabetes Prevention Program. The effect of lifestyle intervention and metformin on preventing or delaying diabetes among women with and without gestational diabetes: the Diabetes Prevention Program outcomes study 10-year follow-up. Found inside – Page 1083The Diabetes Prevention Program (DPP): description of lifestyle ... Eight-year weight losses with an intensive lifestyle intervention: the look AHEAD study. 18. The C allele of ATM rs11212617 does not associate with metformin response in the Diabetes Prevention Program. There were some changes to the treatments each group received: DPPOS participants who developed diabetes remained in the study and received additional care from their own physicians if good blood glucose control could not be maintained. Mather KJ, Christophi CA, Jablonski KA, Knowler WC, Goldberg RB, Kahn SE, Spector T, Dastani Z, Waterworth D, Richards JB, Funahashi T, Pi-Sunyer FX, Pollin TI, Florez JC, Franks PW; Diabetes Prevention Program Research Group. Diabetes Care 2013;36:2027-34. Diabet Med. Erratum in: Ann Intern Med. As you review each strategy, ask participants for examples and allow time for discussion: 1. Study record managers: refer to the Data Element Definitions if submitting registration or results information. Found inside – Page 311“Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin.” NEnglJMed 346 (2002): 393–403. The Look AHEAD Study was launched ... Diabetes Prevention Program Research Group Lifestyle and Metformin Ameliorate Insulin Sensitivity Independently of the Genetic Burden of Established Insulin Resistance Variants in Diabetes Prevention Program Participants Diabetes 65 2: ... the Look AHEAD Trial Diabetes Care 37 6: 1544-53; 2014 PMC4030096. Comparison among criteria to define successful weight-loss maintainers and regainers in the Action for Health in Diabetes (Look AHEAD) and Diabetes Prevention Program trials. 2003 ; 24:610–628. Similar proportions of each DPP group joined the DPPOS and remained in their original groups. Diabetes Prevention Program (DPP) Research Group. Diabetes Prevention Program Research Group. The answer is yes, they both can. Found inside – Page 456Look AHEAD Research Group; Reduction in weight and cardiovascular disease risk factors in ... The Indian Diabetes Prevention Programme shows that lifestyle ... J Gerontol A Biol Sci Med Sci. Metformin for diabetes prevention: insights gained from the Diabetes Prevention Program/Diabetes Prevention Program Outcomes Study. The Diabetes Prevention Program (DPP) and Look AHEAD (Action for Health in Diabetes) trials are long-term randomized clinical trials that have the potential to direct diabetes care and medical nutrition therapy for obesity, prediabetes, and type 2 diabetes both now and in the future. Metformin was effective for all participating racial and ethnic groups and both men and women. Epub 2012 Jun 9. eCollection 2020. Plan pleasures other than food and drink. Found inside – Page 257Diabetes Prevention Program and Look AHEAD The Diabetes Prevention Program (DPP) compared the efficacy of three treatments in preventing type 2 diabetes and ... Impact of diagnosis of diabetes on health-related quality of life among high risk individuals: the Diabetes Prevention Program outcomes study. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. Diabetes Prevention Program Research Group, Orchard TJ, Temprosa M, et al. Comprehensive Analysis of Established Dyslipidemia-Associated Loci in the Diabetes Prevention Program. 10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program … For most of us, staying active on holidays isn t easy. Fill one quarter with carb foods. The NIDDK built on the success of the DPP by funding additional research to make modified versions of the DPP Lifestyle Change Program that are more cost-effective and more easily available to the tens of millions of Americans at risk for type 2 diabetes. Dietary Plan ... Diabetes Prevention Program • Can a 7% reduction in initial weight, combined JAMA Netw Open. Of the 3,149 surviving participants, 2,776 (88 percent) joined the DPPOS. Sylvetsky AC, Edelstein SL, Walford G, Boyko EJ, Horton ES, Ibebuogu UN, Knowler WC, Montez MG, Temprosa M, Hoskin M, Rother KI, Delahanty LM; Diabetes Prevention Program Research Group. Psychoneuroendocrinology. Jablonski KA, McAteer JB, de Bakker PI, Franks PW, Pollin TI, Hanson RL, Saxena R, Fowler S, Shuldiner AR, Knowler WC, Altshuler D, Florez JC; Diabetes Prevention Program Research Group. Papandonatos GD, Pan Q, Pajewski NM, Delahanty LM, Peter I, Erar B, Ahmad S, Harden M, Chen L, Fontanillas P; GIANT Consortium, Wagenknecht LE, Kahn SE, Wing RR, Jablonski KA, Huggins GS, Knowler WC, Florez JC, McCaffery JM, Franks PW; Diabetes Prevention Program and the Look AHEAD Research Groups. Found inside – Page 601Diabetes Care 2012;35(2):363–6. Papandonatos GD, Pan Q, Pajewski NM, et al, Diabetes Prevention Program and the Look AHEAD Research Groups. Participants from the DPP Lifestyle Change Program ages 60 and older had a delay in the development of diabetes by 49 percent. 2008 Dec;51(12):2214-23. doi: 10.1007/s00125-008-1158-x. Epub 2011 Dec 16. Study Size, Participant Demographics, Study Design, and Follow-Up One version tested in YMCAs is now widely available in the United States through a partnership with the CDC’s National Diabetes Prevention Program. - Diabetes Prevention Program - Look AHEAD • Disseminating Lifestyle Modification ... Diabetes Prevention Research Group. Maruthur NM, Ma Y, Delahanty LM, Nelson JA, Aroda V, White NH, Marrero D, Brancati FL, Clark JM; Diabetes Prevention Program Research Group. Found inside – Page 308... programs like the Diabetes Prevention Program (DPP) and Look AHEAD have ... The DPP looked at over 3,000 individuals with impaired glucose tolerance and ... Epub 2009 Jan 8. 2007 Dec;50(12):2451-60. Testosterone and depressive symptoms among men in the Diabetes Prevention Program. Diabetes Care. 2012 Sep;35(9):1864-7. Look AHEAD does nothing to … participants from the DPP Lifestyle Change Program continued to have a delay in the development of diabetes by 27 percent compared with participants who took a placebo. Mather KJ, Kim C, Christophi CA, Aroda VR, Knowler WC, Edelstein SE, Florez JC, Labrie F, Kahn SE, Goldberg RB, Barrett-Connor E; Diabetes Prevention Program. 2015 Dec;64(12):4312-21. doi: 10.2337/db15-0441. Arch Intern Med 2010;170:1566-75. Epub 2012 Nov 5. They also challenge us with unique social cues. Gupta DK, Walford GA, Ma Y, Jarolim P, Wang TJ; DPP Research Group. Epub 2015 Apr 8. J Clin Endocrinol Metab. Look AHEAD (Action for Health in Diabetes) Initiated: Started in 2000 and ended in 2012 ... Diabetes Prevention Program Research Group, Knowler WC, Fowler SE, et al. Action for Health in Diabetes (Look AHEAD) Study – Look AHEAD used an intensive lifestyle change program modeled on the DPP Lifestyle Change Program to study how diet and physical activity affect heart attack, stroke, and cardiovascular disease-related death in people who already had type 2 diabetes. ... C Look for free time (10 to 15 minutes) during the day. The Program worked particularly well for participants ages 60 and older, lowering their chances of developing type 2 diabetes by 71 percent. The new program will be called MDPP, or Medicare Diabetes Prevention Program. Diabetes was diagnosed on the basis of an annual oral glucose-tolerance test or a semiannual fasting plasma glucose test, according to the 1997 criteria of the American Diabetes Association. 2015 Mar;64(3):989-98. doi: 10.2337/db14-0333. Found insideIn such cases, early intervention to prevent metabolic complications is ... gained in the Diabetes Prevention Program (DPP) and the Look AHEAD trial, ... Diabetes Prevention Program (DPP) 1 Diabetes Prevention Program (DPP) 2 Diabetes Prevention Program Outcomes Study (DPPOS) 3 News Releases and Reports INTRODUCTION. Franks PW, Jablonski KA, Delahanty LM, McAteer JB, Kahn SE, Knowler WC, Florez JC; Diabetes Prevention Program Research Group. Comparison among criteria to define successful weight-loss maintainers and regainers in the Action for Health in Diabetes (Look AHEAD) and Diabetes Prevention Program trials. Diabetes. Clin Diabetes Endocrinol. Depression as a predictor of weight regain among successful weight losers in the diabetes prevention program. Knowler WC, Barrett-Connor E, Fowler SE, et al. Partners make it easier for people at risk for type 2 diabetes to participate in evidence-based lifestyle change programs to reduce their risk of type 2 diabetes. Review the following strategies (summarized on the handout). 2017 Dec;40(12):1668-1677. doi: 10.2337/dc17-1116. Perreault L, Pan Q, Aroda VR, Barrett-Connor E, Dabelea D, Dagogo-Jack S, Hamman RF, Kahn SE, Mather KJ, Knowler WC; Diabetes Prevention Program Research Group. Based on the results of this prevention intervention, the Look AHEAD (Action for Health in Diabetes) study is currently underway to test the effects of similar lifestyle interventions in the treatment of 5,145 men and women who have already been diagnosed with type 2 diabetes. Diabetes Care. 2015 Apr;77(3):303-10. doi: 10.1097/PSY.0000000000000156. Florez H, Ma Y, Crandall JP, Perreault L, Marcovina SM, Bray GA, Saudek CD, Barrett-Connor E, Knowler WC; Diabetes Prevention Program Research Group. doi: 10.1371/journal.pone.0229280. 2002;346:393-403 . Found inside – Page 111Reference: Look AHEAD Research Group. ... support of exercise in the prevention of type 2 diabetes come from a 6 yr clinical trial in which subjects with ... Pennington Biomedical is a research leader in diabetes prevention and management and has participated in all the landmark clinical trials including the Diabetes Prevention Program (DPP) and the Look AHEAD (Action for Health in Diabetes) Study, both funded by the National Institutes of Health. The DPPOS is following DPP participants to see if participants who took part in the DPP Lifestyle Change Program or who are continuing to take metformin have a delay in the development of type 2 diabetes over time and if they experience fewer health problems such as cancer, cardiovascular diseases, nerve damage, kidney disease, eye disease, and age-related health problems such as trouble with physical function and difficulties with thinking or memory. Studies a U.S. FDA-regulated Drug Product: Studies a U.S. FDA-regulated Device Product: Development of diabetes [ Time Frame: Up to 5 years ], Impaired glucose tolerance (fasting plasma glucose 95-125 mg/dL and 2hr plasma glucose 140-199 mg/dL), Underlying disease likely to limit life span and/or increase risk of interventions, Conditions or behaviors likely to effect conduct of the DPP, Diabetes or disordered glucose metabolism. Currently she is Chairman of Look AHEAD, a 12-year NIH clinical trial of weight loss in 5,000 adults with type 2 diabetes. Control Clin Trials . Merino J, Jablonski KA, Mercader JM, Kahn SE, Chen L, Harden M, Delahanty LM, Araneta MRG, Walford GA, Jacobs SBR, Ibebuogu UN, Franks PW, Knowler WC, Florez JC; Diabetes Prevention Program Research Group. PMID: 23275375. To date, the DPPOS has shown that participants who took part in the DPP Lifestyle Change Program or are taking metformin continue to prevent or delay type 2 diabetes for at least 15 years. Epub 2017 Aug 2. Review. participants from the DPP Lifestyle Change Program and participants who continued to take metformin or took a placebo all improved their risk factors for cardiovascular diseases, such as high blood pressure and cholesterol. Found insideLook AHEAD Research Group (2003) Look AHEAD (Action for Health in ... (2004) Dietary intake in the Diabetes Prevention Program cohort: baseline and 1year ... Epub 2016 Oct 26. Session 5 – Diabetes Prevention and Management 9:45 AM - 10:30 AM The Experience with the Diabetes Prevention Program and Look Ahead Study: The intensive lifestyle intervention was modeled on the landmark Diabetes Prevention Program (DPP). the DPP Lifestyle Change Program was shown to be cost-effective and metformin was shown to be cost-saving. Diabetes Care. Diabetes Care. Found inside – Page 324Diabetes Prevention Program and the Look Ahead study also used additional behavioral interventions to provide support, motivation and feedback to the ... 2019 Feb 1;104(2):328-336. doi: 10.1210/jc.2018-01416. 2002 Feb 7;346(6):393-403. Franks PW, Christophi CA, Jablonski KA, Billings LK, Delahanty LM, Horton ES, Knowler WC, Florez JC; Diabetes Prevention Program Research Group. DOPM investigators also have a strong program of interventional research in cardiometabolic disease, serving as a site in several large multi-center cardiovascular disease intervention studies including the Look AHEAD (Action for Health in Diabetes) study, Systolic Blood Pressure Intervention Trial (SPRINT), and others. Found inside – Page 473Effect of the look ahead study intervention on medication use and related cost ... over 15-year follow-up: the diabetes prevention program outcomes study. His research programs have included a 43-year longitudinal study that uncovered risk factors for type 2 diabetes and its complications, and several groundbreaking, multi-center studies, such as the Diabetes Prevention Program (DPP), the DPP Outcomes Study (DPPOS) and Action for Health in Diabetes (Look AHEAD) clinical trials. Kanaya AM, Santoyo-Olsson J, Gregorich S, Grossman M, Moore T, Stewart AL. The DPP looked at whether the DPP Lifestyle Change Program or taking metformin would delay or prevent type 2 diabetes. TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program. 2015 Jun;58(6):1198-202. doi: 10.1007/s00125-015-3565-0. Diabetes Care. Changes in albumin excretion in the diabetes prevention program. Depressive symptoms, antidepressant medication use, and new onset of diabetes in participants of the diabetes prevention program and the diabetes prevention program outcomes study. The new program will be called MDPP, or Medicare Diabetes Prevention Program. Cardenas A, Hivert MF, Gold DR, Hauser R, Kleinman KP, Lin PD, Fleisch AF, Calafat AM, Ye X, Webster TF, Horton ES, Oken E. Associations of Perfluoroalkyl and Polyfluoroalkyl Substances With Incident Diabetes and Microvascular Disease. What s more, holidays may involve inactive habits that have developed over many years. Assessing gene-treatment interactions at the FTO and INSIG2 loci on obesity-related traits in the Diabetes Prevention Program. 2015 Apr;100(4):1646-53. doi: 10.1210/jc.2014-3761. (2019). Long-Term Weight Loss With Metformin or Lifestyle Intervention in the Diabetes Prevention Program Outcomes Study. Found inside – Page 169In adults, evidence-based behavioral weight loss programs have been shown to ... of 7 to 10% (Diabetes Prevention Program Research Group, 2002; Look AHEAD ... Keywords provided by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK): Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number): Why Should I Register and Submit Results? participants who took part in the DPP Lifestyle Change Program continued to have a delay in the development of diabetes by 34 percent—and developed diabetes about 4 years later—compared with participants who took a placebo. Diabetes Care. Epub 2008 Jun 10. Regression From Prediabetes to Normal Glucose Regulation and Prevalence of Microvascular Disease in the Diabetes Prevention Program Outcomes Study (DPPOS). The Diabetes Prevention Program (DPP) and its follow-up, the Diabetes Prevention Program Outcomes Study, and Look AHEAD (Action for Health in Diabetes), are long-term randomized clinical trials that have potential to direct diabetes care and medical nutrition therapy for obesity, prediabetes, and type 2 diabetes (T2DM) both now and in the future. The DPP was a randomized, controlled clinical trial conducted at 27 clinical centers around the United States from 1996 to 2001. POSITION SUMMARY This position is located at the Northern Navajo Medical Center Diabetes Prevention Clinic in Shiprock, NM. Diabetes Prevention Program Research Group, Knowler WC, Fowler SE, et al. Florez JC, Jablonski KA, Taylor A, Mather K, Horton E, White NH, Barrett-Connor E, Knowler WC, Shuldiner AR, Pollin TI; Diabetes Prevention Program Research Group. The trial enrolled 3,234 participants; 55 percent were Caucasian, and 45 percent were from minority groups at high risk for the disease, including African American, Alaska Native, American Indian, Asian American, Hispanic/Latino, or Pacific Islander. Effect of regression from prediabetes to normal glucose regulation on long-term reduction in diabetes risk: results from the Diabetes Prevention Program Outcomes Study. Found inside – Page 524diabetes with mean LDL cholesterol levels less than 118 mg/dL at study entry assigned ... studied in the Diabetes Prevention Program and Look AHEAD studies, ... Kriska AM, Rockette-Wagner B, Edelstein SL, Bray GA, Delahanty LM, Hoskin MA, Horton ES, Venditti EM, Knowler WC; DPP Research Group. Epub 2014 Oct 2. Epub 2013 May 26. Diabetes Care. Diabetes Prevention Program Research Group. 2019 May 21;170(10):682-690. doi: 10.7326/M18-1605. Racial/ethnic differences in circulating natriuretic peptide levels: The Diabetes Prevention Program. Dr. Marrero DG, Ma Y, de Groot M, Horton ES, Price DW, Barrett-Connor E, Carnethon MR, Knowler WC; Diabetes Prevention Program Research Group. Diabetes Care. BMJ Open Diabetes Res Care. J Clin Endocrinol Metab. Epub 2016 Jun 15. Look AHEAD (Action for Health in Diabetes): design and methods for a clinical trial of weight loss for the prevention of cardiovascular disease in type 2 diabetes. 2013 Jan;36(1):34-40. doi: 10.2337/dc12-0733. Epub 2019 Apr 23. Diabetes. PLoS One. The Diabetes Prevention Support Center (DPSC) of the University of Pittsburgh is committed to reducing the burden of diabetes by providing education and training for health care providers in delivery of healthy lifestyle intervention, and support to people who are at risk for diabetes and its complications. Diabetes Care, 42, 601-608. All 3,149 surviving participants of DPP groups were eligible for the DPPOS, including those with and without diabetes. Look AHEAD Lifestyle Program (Adapted from The Diabetes Prevention Program ) Staying Active on Holidays. Participants who did not develop diabetes had a 28 percent lower rate of small blood vessel problems compared with participants who developed diabetes. The Look AHEAD (Action for Health in Diabetes) study was designed to assess the effects of an intensive lifestyle intervention (ILI) on clinically important health outcomes in overweight/obese individuals with type 2 diabetes . Knowler WC, Barrett-Connor E, Fowler SE, Hamman RF, Lachin JM, Walker EA, Nathan DM; Diabetes Prevention Program Research Group. HbA1c as a predictor of diabetes and as an outcome in the diabetes prevention program: a randomized clinical trial. Common variants in genes encoding adiponectin (ADIPOQ) and its receptors (ADIPOR1/2), adiponectin concentrations, and diabetes incidence in the Diabetes Prevention Program. AHEAD14 and Diabetes Prevention Program (DPP)23 session materials and included the first 19 sessions from the original Look AHEAD LI. Psychosom Med. 2014 Feb;23(1):75-88. doi: 10.1007/s11136-013-0436-3. Herman WH, Pan Q, Edelstein SL, Mather KJ, Perreault L, Barrett-Connor E, Dabelea DM, Horton E, Kahn SE, Knowler WC, Lorenzo C, Pi-Sunyer X, Venditti E, Ye W; Diabetes Prevention Program Research Group. Use the time to be CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. The government plans to create a diabetes prevention program for Medicare and Medicaid beneficiaries with prediabetes. 2020 Sep 15;173(6):508. Psychosom Med. The Look AHEAD cohort will comprise 5000 overweight or obese participants with type 2 diabetes, aged 45-75. A High-Carbohydrate, High-Fiber, Low-Fat Diet Results in Weight Loss among Adults at High Risk of Type 2 Diabetes. 15 Found inside – Page 295 Diabetes Prevention Program Research Group. ... 6 Look AHEAD Research Group: Reduction in weight and cardiovascular disease risk factors in individuals ... Researchers will evaluate the efficacy of a lifestyle intervention and a pharmacological intervention in preventing or delaying Type 2 diabetes in persons with impaired glucose tolerance (IGT). Epub 2020 Nov 10. to try to prevent diabetes. Erratum in: Diabetologia. Translating the Diabetes Prevention Program into American Indian and Alaska Native communities: results from the Special Diabetes Program for Indians Diabetes Prevention demonstration project. The Impact of Physical Activity on the Prevention of Type 2 Diabetes: Evidence and Lessons Learned From the Diabetes Prevention Program, a Long-Standing Clinical Trial Incorporating Subjective and Objective Activity Measures. Long-term Effects of Metformin on Diabetes Prevention: Identification of Subgroups That Benefited Most in the Diabetes Prevention Program and Diabetes Prevention Program Outcomes Study. She has been an investigator for various US National Institutes of Health-sponsored studies, including Pounds Lost, DASH (Dietary Approaches to Stop Hypertension), DPP (Diabetes Prevention Program) and the Look AHEAD study. J Gen Intern Med. Delahanty LM, Pan Q, Jablonski KA, Watson KE, McCaffery JM, Shuldiner A, Kahn SE, Knowler WC, Florez JC, Franks PW; Diabetes Prevention Program Research Group. Taking metformin, a safe and effective generic medicine to treat diabetes, was also found to prevent the disease, though to a lesser degree. In terms of the specific intervention, the Look AHEAD trial intensive intervention diverged from that of the Diabetes Prevention Program (DPP) in that there were more counseling sessions extending over a longer duration with both individual and group treatment in addition to the meal replacements that were provided. Dietary Plan ... Diabetes Prevention Program • Can a 7% reduction in initial weight, combined The intensive intervention of Look AHEAD was based on the methods of the Diabetes Prevention Program. 2002;346:393-403 . The Diabetes Prevention Program (DPP) and its followup, the Diabetes Prevention Program Outcomes Study (DPPOS), and Look AHEAD (Action for Health in Diabetes), are long-term randomized clinical trials that have potential to direct diabetes care and medical nutrition therapy for obesity, prediabetes and type 2 diabetes (T2DM) now and in the future. Berger SE, Huggins GS, McCaffery JM, Lichtenstein AH. Multi-tiered efforts to prevent diabetes are needed for both high risk individuals and the overall population. Found inside – Page 396Brussels, Belgium: International Diabetes Federation; 2019. 2. ... in individuals with type 2 diabetes mellitus: four-year results of the look AHEAD trial. She was responsible for designing and implementing the lifestyle intervention in the Diabetes Prevention Program, an NIH multi-center trial that provides the strongest proof to date of health benefits of weight loss. 2009 Jul;52(7):1456. CDC twenty four seven. Metformin, Lifestyle Intervention, and Cognition in the Diabetes Prevention Program Outcomes Study. Epub 2014 Oct 21. Found inside – Page 9Lifestyle interventions, as studied in both the Diabetes Prevention Program (DPP) and the Action for Health in Diabetes Study (Look AHEAD), ... 2014 Mar;57(3):485-90. doi: 10.1007/s00125-013-3133-4. Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00004992. 2015 Sep 2;1:9. doi: 10.1186/s40842-015-0009-1. Diabetes Care. Read our, ClinicalTrials.gov Identifier: NCT00004992, Interventional J Clin Endocrinol Metab. 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