PPIs can cause Digestion Issues . When the stomach does not have enough acid it can have trouble breaking down food. Hi, Protonix can cause anxiety and it has been reported by many who take that medication. Then I was diagnosed with anxiety with all the added symptoms after taking PPI. A total of 3,386 people (6.4 percent) reported a positive COVID-19 test. Actually when I was diagnosed with GERD i was feeling horrible, anxiety bloating and feeling hungry but can't eat. Treatment with proton-pump inhibitors (PPIs) might be associated with neuropsychological side effects. I was taking PPI last June after my ER visit. 5. People who reported using a PPI once daily were 2.15 times more likely to report a … The high dose of Protonix — not irritable bowel syndrome — is likely the cause of your diarrhea. At the same time, PPIs are among the most overused and misused medicines in America. Always consult your personal physician for complete evaluation of your health problem. One of the most serious side effects of proton pump inhibitors (PPI) is C. difficile diarrhea. Infrequent adverse effects include rash, itch, flatulence, constipation, anxiety, and depression. Mood was assessed by the 30-item Geriatric Depression Scale (GDS) in all 344 inhabitants of Tuscani … People taking a PPI were about twice as likely as other individuals to report depression or anxiety. All you can do is experiment and test, try skipping a couple PPI doses , try anxiety management, see what works and what doesn't. I called my doctor and they wrote me off right away saying the drug should be out of my system and maybe I suddenly developed anxiety (never had any issue with anxiety in my entire life) and that I … That said, I'm taking a shot in the dark here. Studies have found many people take proton pump inhibitors for the wrong condition. Proton pump inhibitors may also interact with other drugs a person is already taking. Normally, stomach acid creates a fairly inhospitable environment for bacteria, but if acid levels are reduced by PPIs, the bacteria count can go up. The connection between GERD and Anxiety is mysterious and non-fictional, there's a lot of correlation. According to the federal agency, PPIs may lead to low levels of magnesium in the blood (hypomagnesemia), especially if taken for more than one year. AFAIK It's fairly safe to skip PPI doses or try other hearburn drugs. In rare cases, PPI use may cause idiosyncratic reactions such as erythema multiforme, pancreatitis, StevensJohnson syndrome, and acute interstitial nephritis. The thinking is that in people with GERD who take PPIs, bacteria-laden stomach contents may travel up the esophagus and then get inhaled into the windpipe and lungs, where the bacteria cause pneumonia. Stomach acid is crucial for health and digestion. The FDA has issued several safety warnings about the use of prescription-strength PPIs and lower-dose OTC forms of the medicine. ===== The information provided is for patients’ education only and is not a medical advice. I’ve seen this in many older patients, and the Food and Drug Administration recently issued a safety alert about these drugs and diarrhea that doesn’t go away. We examined the association between use of PPIs and depressive symptoms in an elderly population. If it persists and is troublesome, the medication has to be discontinued. Hi DCALL, yes PPI (Nexium) had caused me more Anxiety. I did some more research and found that protonix can cause a vitamin B-12 deficiency and anxiety. Alternatives to proton pump inhibitors may not work for some conditions PPIs treat.

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